Dialkyl Ether Formation by Nickel-Catalyzed Cross-Coupling of Acetals and Aryl Iodides

Nickel-Catalyzed Reductive Cross-Coupling of (Hetero)Aryl Iodides with Fluorinated Secondary Alkyl Bromides.

A mild and efficient nickel-catalyzed reductive cross-coupling between fluorinated secondary alkyl bromides and (hetero)aryl iodides is described. The use of FeBr2 as an additive successfully overcomes the hydrodebromination and β-fluorine elimination of fluorinated substrates and allows the efficient synthesis of a wide range of trifluoromethyl and difluoroalkyl containing aliphatic compounds ...

Carbogallation of alkynes using gallium tribromide and silyl ketene acetals and synthetic application to cross-coupling with aryl iodides.

CuO hollow nanosphere-catalyzed cross-coupling of aryl iodides with thiols

New functionalized CuO hollow nanospheres on acetylene black (CuO/AB) and on charcoal (CuO/C) have been found to be effective catalysts for C-S bond formation under microwave irradiation. CuO catalysts showed high catalytic activity with a wide variety of substituents which include electron-rich and electron-poor aryl iodides with thiophenols by the addition of two equivalents of K2CO3 as base ...

Palladium-catalyzed cross-coupling of aryl or vinyl iodides with ethyl diazoacetate.

Palladium catalyzed cross-coupling reaction has been developed into one of the most powerful methods for the formation of C-C bonds.1 Recently, remarkable progress has been made in the Pdcatalyzed cross-coupling reactions with carbon nucleophiles derived from active methylene compounds,1d ketones,2 esters,3 amides,4 and nitriles.5 Hydrazones have also been applied in this type of reactions as a...

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles.

A Ni-catalyzed asymmetric reductive cross-coupling of heteroaryl iodides and α-chloronitriles has been developed. This method furnishes enantioenriched α,α-disubstituted nitriles from simple organohalide building blocks. The reaction tolerates a variety of heterocyclic coupling partners, including pyridines, pyrimidines, quinolines, thiophenes, and piperidines. The reaction proceeds under mild ...